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Nehrig, N., Prout, T.A., & Aafjes-van Doorn, K. (2019). Whose anxiety are we treating, anyway? Journal of Clinical Psychology. Online first publication.

Evidence-based practice (EBP) in psychotherapy is defined by the American Psychological Association as the deliberate integration of: (1) the research evidence, (2) clinician expertise in making treatment decisions, and (3) client characteristics, preferences, and culture. The EBP statement was meant to supplant an older model of prescriptive psychotherapy practice that resulted in the creation of lists of empirically-supported treatments (EST). The ESTs were defined as: (1) manualized therapies, (2) shown to be efficacious in randomized controlled trials, (3) for patients with a specific diagnosed mental disorder. However, manualized therapies are not necessarily more effective than non-manualized treatments, and patients in randomized controlled trials may not represent those typically seen by therapists in everyday practice. Although EBPs are the current standard by which psychotherapists should practice, many therapists and organizations focus almost exclusively on the first of the EBP criteria (the research evidence of ESTs) to the exclusion of the second and third criteria (clinician expertise, and patient characteristics, preferences, and culture). In this review article, Nehrig and colleagues speculated about why this is the case by asking: “whose anxiety are we treating?” They argued that manualized therapies identified as ESTs reduce therapists’ anxiety caused by: uncertainty about treatment outcomes, the emotional toll of providing psychotherapy to people who are suffering, and the negative emotions (anxiety, despair, cynicism) that sometimes arises in therapists from the work. Nehrig and colleagues argued that ESTs provide therapists with a sense of control and certainty, while limiting therapists’ attention on relational challenges in the work of therapy. However, this emphasis on ESTs comes at a cost for therapists and patients. Therapists may not focus on developing skills to manage the relational challenges inherent in providing psychotherapy, greater certainty may reduce therapists’ engagement in sufficient self-reflection, and therapists may attend only to patients’ symptoms and not to the patient as a whole person. Nehrig and colleagues also discuss the preference for ESTs among institutions, insurance companies, and government funders of psychotherapy. ESTs reduce anxiety in these contexts because ESTs are seen by managers as methods to enhance accountability and standardization of treatment, to uphold standards of care, and to reduce potential liability. The short-term nature of most ESTs also assuages economic concerns for institutions and funders who wish to manage costs. However, this emphasis on short term manualized treatment also reduces psychotherapy from a complex interpersonal process with inherent uncertainty to one that resembles a clear-cut medical procedure that encourages top-down decision-making about clinical practice.

Practice Implications

Anxiety about the complexity of psychotherapy can cause therapists, institutional managers, and government funders to place greater value on ESTs rather than on clinical expertise of the therapist and patient characteristics. Patient characteristics, preferences, and culture are related to developing the therapeutic alliance and to patient outcomes. Astute therapists can learn to adjust their interventions to these patient characteristics, which may mean using clinical judgement to alter or deviate from a prescriptive manual. An EBP approach that integrates research, clinical expertise, and patient characteristics allows therapists to take into account transtheoretical factors known to affect outcomes like the therapeutic alliance, repairing alliance ruptures, empathy, and to use their clinical expertise to adjust their interpersonal stances to relevant patient characteristics, preferences, and culture.

Ravitz, P., Watson, P., Lawson, A., Constantino, M.J., Bernecker, S., Park, J., & Swartz, H.A. (2019). Interpersonal Psychotherapy: A scoping review and historical perspective (1974-2017). Harvard Review of Psychiatry, 27, 165-179.

Interpersonal Psychotherapy (IPT) focuses on relationships and emotions, and emphasizes stressful interpersonal loss, life changes, relationship disputes, and social isolation as the causes and maintenance factors related to depression and other disorders. The IPT is predicated on the importance of relationships for survival and the bidirectional links between depression and problems with relationships and social support. IPT was first manualized in 1974 and used as a comparison condition in studies of pharmacotherapy for depression. Contrary to expectations, IPT did just as well as antidepressant medication in early treatment trials, thus giving rise to an important new psychological treatment. This scoping review by Ravitz and colleagues summarizes the development of IPT over the past 40 years. The review identified over 1000 articles of IPT, 133 of which were randomized controlled trials. Following the initial trials in the 1970s, IPT was included in the Treatment of Depression Collaborative Research Program in the 1980s, funded by the National Institute of Mental Health in the United States. This was the largest trial of its kind whose results indicated that patients with high baseline depression did best with medications followed by IPT, whereas CBT did not show significant advantage over the placebo condition. The 1990s to the mid-2000s saw a precipitous increase in randomized controlled trials of IPT in which IPT was: compared to other therapies, compared to medications, and/or provided in combination with medications. In addition, treatment trials of group IPT were conducted in low- and middle-income countries. These studies led the World Health Organization to publish and disseminate a group IPT manual. More recent research in the past decade has seen IPT offered in different formats (individual, telephone, group, internet), for different populations (adolescents, perinatal women, late-life), and in a variety of low- and high-income countries. Currently, there is good research support for the efficacy of IPT for depression, eating disorders, bipolar disorder, PTSD, and anxiety.

Practice Implications

Relationships play an important role in determining health, disease, vulnerability, recovery, and resilience. Because of the universal importance of relationships, IPT is relevant to mental health care across cultures and populations. Therapists should consider the importance of relationship loss and grief, role transitions throughout the lifespan, persistent conflicts in relationships, and social isolation when treating patients with depression and other mental disorders.

Karver, M. S., De Nadai, A. S., Monahan, M., & Shirk, S. R. (2018). Meta-analysis of the prospective relation between alliance and outcome in child and adolescent psychotherapy. Psychotherapy, 55(4), 341-355.

Over the past decades there has been increasing research on the efficacy of psychotherapy for children and adolescents, but outcomes have not always been positive. Treatment of children and adolescents comes with challenges that are unique from those experienced in therapy of adults. For example, unlike most adults, children and adolescents may not be the ones to choose to attend therapy - that decision is often made by adults in their lives. Furthermore, psychotherapists must also develop and maintain a collaborative relationship with parents, on whom the therapist and child/adolescent rely in order to be able to engage in treatment. Because of the unique characteristics of working with children and adolescents, negotiating, developing, maintaining, and repairing the therapeutic alliance is potentially complex. The therapeutic alliance is defined as an agreement on tasks of therapy, an agreement on goals of therapy, and the relational bond between therapist and client. In this meta-analysis, Karver and colleagues reviewed 28 studies of psychotherapy with children and adolescents. The mean age was about 12 years, most children/adolescents had internalizing problems, but others had problems with externalizing behaviors, and substance abuse. Almost two thirds of the studies involved a version of behavior or cognitive behavioral therapy. The therapeutic alliance was measured from the perspective of the client, therapist, and/or the parent. The overall mean effect size of the alliance-outcome relationship was small to moderate: r = .19 (p < .01, 95% confidence interval [CI] [0.13, 0.25]). Larger effect sizes were seen in those therapies of children and adolescents with internalizing disorders (r = .19), and when the therapist – parent alliance was measured and correlated with outcomes (r = .30). In other words, a positive alliance was most important for internalizing disorders, and for the relationship between therapist and parent.

Practice Implications

The findings of this meta-analysis indicate that the therapeutic alliance, especially with the parent, is important to the outcomes of children and adolescents in psychotherapy. Clinicians should not only develop an alliance with the youth, but also with the parent/caregiver. Therapists should also consider measuring the alliance regularly during therapy as a means of heading off any ruptures (with the youth or the parent) that might endanger the therapy. The authors recommended using the Therapeutic Alliance Scale for Children – Revised with children/adolescents, and the Working Alliance Inventory with parents.

Hill, C. E., Knox, S., & Pinto-Coelho, K. G. (2018). Therapist self-disclosure and immediacy: A qualitative meta-analysis. Psychotherapy, 55(4), 445-460.

Different writers and theorists in psychotherapy have disagreed on the need for or the wisdom of therapists disclosing about themselves during therapy. Recently, however, both humanistic therapists and some psychodynamic therapists tend to see therapist self-disclosure or immediate discussion of the therapeutic relationship more positively. Therapist self-disclosure is a therapist statement that reveals something personal about the therapist (“That makes me angry too”). On the other hand, immediacy refers to comments about and processing the therapeutic relationship by client and therapist in the here and now (“You said that people inevitably let you down, I wonder if you expect that I will let you down too”). Immediacy, also known as metacommunication, is particularly useful to address therapeutic alliance ruptures. In this qualitative meta-analysis, Hill and colleagues (2018) examined research that studied the effects of therapist disclosures and immediacy on subsequent client processes right after the disclosure or immediacy occurred. The authors included in their review 21 studies with a total sample of 184 cases. Five studies with 99 cases looked specifically at the effect of therapist disclosure. Therapist self-disclosure occurred relatively infrequently in 0% to 4% of all therapist responses. The most frequently occurring subsequent processes after therapist disclosure included an enhanced therapy relationship (reported in 64% of studies), greater client insight (reported in 46% of studies), and improved client mental health (reported in 45% of studies). Negative effects of therapist disclosure included negative client feelings or reactions (reported in 30% of studies) and impaired therapeutic relationship (reported in 16% of studies). Fifteen studies with 78 cases looked specifically at immediacy. Therapists used immediacy more extensively in between 12% to 38% of cases. The most frequently occurring subsequent processes following immediacy included an enhanced therapy relationship (reported in 40% of studies), and increased client self-disclosure (reported in 40% of studies). Negative effects of immediacy included a negative impact for the therapist (reported in 11% of studies) that referred to a heightened sense of therapist vulnerability.

Practice Implications

Reviews and theoretical guidelines stress that therapists should sparingly and deliberately use self-disclosure and immediacy. In fact, this review by Hill and colleagues indicated that therapist self-disclosure is relatively rare, whereas immediacy might be more common. Therapists might consider self-disclosure when the client is feeling alone and in need of support. But, as Hill and colleagues indicate, therapists must be thoughtful and strategic about self-disclosure, therapists should disclose only personally resolved material, and therapists must focus their disclosures exclusively on the client’s needs. On the other hand, immediacy may be a useful strategy to negotiate and address problems in the therapeutic relationship by talking about interactions and intentions in the relationship (i.e., metacommunicate about the relationship). Therapists have to consider that immediacy may require lengthy processing, and therapists should be attentive to the role of countertransference and seek consultation in order to be sure to act in the best interest of the client.

Author email: cehill@umd.edu

Lambert, M. J., Whipple, J. L., & Kleinstäuber, M. (2018). Collecting and delivering progress feedback: A meta-analysis of routine outcome monitoring. Psychotherapy, 55(4), 520-537.

Somewhere between 5% and 10% of adult clients in clinical trials of psychotherapy get worse, and the numbers are likely higher in regular clinical practice. In addition, some therapists are more effective than others, so that some therapists have few clients who get worse whereas others consistently have high rates of poor client outcomes. Unfortunately, therapists have a difficult time assessing their client outcomes. Many therapists are overly optimistic about their clients’ outcomes, and clinicians frequently do not identify when clients get worse. One likely reason for this erroneous assessment of client outcomes is that typically psychotherapists do not have quality information in order to make accurate decisions and predictions. Assessing client outcomes on a regular basis throughout treatment is a difficult and complicated endeavour, and one that is beyond the capacity of most people. So, like other professionals (pilots, air traffic controllers, engineers) psychotherapists can improve their predictions and decision-making if they have access to quality information about their clients’ functioning. One source of such information for psychotherapists could be from the use of routine outcome monitoring. Routine outcome monitoring involves assessing client mental health functioning with reliable psychometric scales throughout the course of treatment, and feeding this information back to therapists who can use the data to adjust what they are doing if necessary. The two most commonly used outcome monitoring tools are the Outcome Questionnaire-45 (OQ-45) which is part of the OQ Analyst Feedback System, and the Outcome Rating Scale (ORS) and Session Rating Scale (SRS) which are part of the Partners for Change Outcome Management System (PCOMS). In this meta-analysis, Lambert and colleagues assessed the effect of regular outcome monitoring with the OQ-45 and the ORS to improve client outcomes. In 15 studies with almost 8,500 participants, the OQ-45 outperformed treatment as usual but with a small effect (SMD = .14, 95% CI [.08, .21]). However, the positive effect of using the OQ-45 with feedback was larger for the 31.2% of clients who were not doing well in therapy (SMD = .33, 95% CI [.25, .41]). Among those studies that used the OQ standardized feedback system that provides recommendations to therapists, the effects were even larger (SMD = .49, 95% CI [.25, .73]). Similarly, in nine studies with over 2,000 participants, the effects of using the PCOMS system had a small to moderate positive effects on client outcomes (SMD = .40, 95% CI [.29, .51]).

Practice Implications

The research evidence supports the use of routine outcome monitoring with the OQ-45 or the PCOMS to improve client outcomes. Quality information that is fed back to clinicians can compensate for the limited capacity that any clinician has to accurately detect a client that is worsening in psychotherapy. The information provided to therapists with these feedback systems can highlight potential problems in the client and identify strain in the therapeutic alliance. This information can sensitise therapists to at-risk clients and situations, and encourage therapists to adjust their interventions or interpersonal stances accordingly.

Author email: lambert.michaelphd@gmail.com

Fonagy, P., Lemma, A., Target, M., O'Keeffe, S., Constantinou, M., Ventura Wurman, T., . . . Pilling, S. (2019). Dynamic interpersonal therapy for moderate to severe depression: A pilot randomized controlled and feasibility trial. Psychological Medicine, 1-10. Online first publication. doi:10.1017/S0033291719000928

Most psychotherapies are equally effective when it comes to treating depression. However, no single therapy is uniformly effective, so that about 50% of patients might improve when it comes to symptom reduction. So, although there is a large evidence base for treatments like CBT, therapists and patients need access to a range of available treatments. There is less research on psychodynamic therapies, although a number of trials and meta-analyses indicate their effectiveness to treat depression. In the United Kingdom (UK), the health system may offer a stepped care program that provides patients with low intensity guided self-help based on a CBT model followed by more intensive treatment with CBT or IPT if patients did not benefit from self-help. The UK health system rarely offers Dynamic Interpersonal Therapy (DIT), and DIT has never been studied in a randomized controlled trial within the UK health system. Fonagy and colleagues designed this randomized controlled trial to test the efficacy of DIT when compared to the CBT-oriented self-help program as offered in the UK. The study also included a smaller randomized sample of those who received the intensive version of CBT for depression. In total, 147 participants with moderate to severe depression were randomly assigned to DIT, CBT guided self-help, or the intensive version of CBT. The DIT is informed by attachment theory and by mentalization theory, and it views depressive symptoms as responses to interpersonal difficulties or perceived attachment threats. The results of the trial showed a significantly greater effect of DIT compared to guided self-help with regard to depressive symptoms, overall symptom severity, social functioning, and quality of life at post-treatment. The patients receiving DIT maintained these gains up to 1-year post-treatment. Over half of DIT patients showed clinically significant improvements, but only 9% who received the CBT-based guided self-help achieved such improvement. There were no significant differences on any of the outcomes between DIT and the more intensive version of CBT.

Practice Implications

One of the benefits of DIT, according to the authors, is that it offers a treatment manual and curriculum that enables those without a lot of background in psychodynamic therapies to deliver it. This makes DIT potentially widely-applicable in publicly funded health systems like in the UK, Canada, and others. DIT may offer yet another effective option of psychotherapy to therapists and their patients who experience depressive symptoms. The study also points to the limits of offering only guided self-help to those with moderate to severe depression.

Author email: p.fonagy@ucl.ac.uk