Blog
The Psychotherapy Practice Research Network (PPRNet) blog began in 2013 in response to psychotherapy clinicians, researchers, and educators who expressed interest in receiving regular information about current practice-oriented psychotherapy research. It offers a monthly summary of two or three published psychotherapy research articles. Each summary is authored by Dr. Tasca and highlights practice implications of selected articles. Past blogs are available in the archives. This content is only available in English.
This month...

…I blog about the treatment of depression, the effects of role induction in psychotherapy, and negative experiences in psychotherapy from clients’ perspective.
Type of Research
Topics
- ALL Topics (clear)
- Adherance
- Alliance and Therapeutic Relationship
- Anxiety Disorders
- Attachment
- Attendance, Attrition, and Drop-Out
- Client Factors
- Client Preferences
- Cognitive Therapy (CT) and Cognitive-Behavioural Therapy (CBT)
- Combination Therapy
- Common Factors
- Cost-effectiveness
- Depression and Depressive Symptoms
- Efficacy of Treatments
- Empathy
- Feedback and Progress Monitoring
- Group Psychotherapy
- Illness and Medical Comorbidities
- Interpersonal Psychotherapy (IPT)
- Long-term Outcomes
- Medications/Pharmacotherapy
- Miscellaneous
- Neuroscience and Brain
- Outcomes and Deterioration
- Personality Disorders
- Placebo Effect
- Practice-Based Research and Practice Research Networks
- Psychodynamic Therapy (PDT)
- Resistance and Reactance
- Self-Reflection and Awareness
- Suicide and Crisis Intervention
- Termination
- Therapist Factors
- Training
- Transference and Countertransference
- Trauma and/or PTSD
- Treatment Length and Frequency
March 2020
Drop-out From Using Smart Phone Apps for Depression is High
Torous, J., Lipschitz, J., Ng, M., & Firth, J. (2020). Dropout rates in clinical trials of smartphone apps for depressive symptoms: A systematic review and meta-analysis. Journal of Affective Disorders, 263, 413-419.
Depression is a leading cause of disability worldwide, and yet more than 50% of people do not have access to adequate therapy. One solution might be to provide individuals with smartphone apps to help screen, monitor, or provide treatment. Smart phones are ubiquitous, and depression apps are one of the most downloaded categories of apps by the public. Research seems to suggest that smartphone apps provide some positive results for members of the public, but these findings are compromised by the high drop-out rates reported in the primary studies. Further, one study found that although many people download the apps, only about 4% actually use them. Whereas smartphone apps appear attractive to the consumer, very few actually make use of and therefore benefit from them. In this systematic review, Torous and colleagues conduct a meta-analysis of drop-out rates from studies that test the use of smart phone apps. They found 18 independent studies representing data from 3,336 participants who received a psychological intervention for depression via a cell phone app, or who were in a placebo control condition. A total of 22 different apps were tested in the studies. Initially, the pooled drop-out rate from the depression app treatment arms appeared to be about 26.2% (95% C.I.=11.34% to 46.75%), which would be in line with average drop-out rates from randomized controlled trials of face to face psychotherapy. But, the authors noted two things. First, the drop-out rate from the placebo control conditions (14.2%; 95% C.I. = 8.236 to 23.406) was almost half as high as that found for the apps. Second, through some sophisticated statistical analyses, they found evidence of “publication bias” in this research area. This means that a number of studies testing these apps likely were completed but never published (i.e., these might be studies funded by an app manufacturer that demonstrated negative findings or high drop-out rates). When the authors statistically adjusted for publication bias, they found that the actual drop-out rate from the apps was about 47.8%. That is, almost half of users did not complete or dropped out of the studies. There were no differences in drop-out between types of interventions (CBT, mindfulness, or others), and studies with larger sample sizes (i.e., better quality studies) had higher drop-out rates.
Practice Implications
Although smartphone apps appear really attractive and may be potentially useful as an adjunct to face to face psychotherapy for depression, their utility is plagued by extremely low usage rates (4%) and high drop-out rates from studies (almost 50%). Leading writers and researchers define psychotherapy as primarily a healing relationship that also includes specific interventions. The key ingredient is the human relationship. Depressed or otherwise troubled individuals cannot (because of feeling demoralized) or will not interact with a machine for healing. One way or another, when it comes to smartphone apps, depressed individuals are voting with their feet. Given these findings, health care providers should consider the ethics of giving a depressed individual only e-therapy as the primary mode of treatment.
February 2020
What do Patients Want from Psychotherapy?
Cuijpers, P. (2020) Measuring success in the treatment of depression: What is most important to patients? Expert Review of Neurotherapeutics, 20, 123-125.
There is lots of evidence now that psychotherapies of various types are efficacious for the treatment of depression. Psychotherapy trials focus largely on depressive symptoms, and define major depression according to psychiatric diagnostic manuals. However, the diagnosis of major depression, for example, is not a unitary construct. That is, it is simply a collection of symptoms and signs that are purported to make up a category of disorder. In fact, people with major depression are quite varied on a whole range of things, like severity, coping style, motivation, attachment style, personality, and extent of comorbidity with other diagnoses. This means that many psychotherapy studies may be focusing on patient outcomes (i.e., reduction of depressive symptoms) that may or may not be important to patients. In this paper, Cuijpers reviews the literature on what patients want from psychotherapy. He found that while symptom reduction was important to patients with depressive disorders, it was not the only outcome they wanted from psychotherapy. Patients also want to have a more fulfilling lives, to return to productive work, to solve conflicts with close loved ones, to learn to live with a chronic disability or disease, to learn to handle the effects of trauma, and other quality of life issues. Fortunately, some studies do report the effects of psychotherapy on quality of life, social functioning, anxiety, hopelessness, and interpersonal problems. However, even these studies treat such outcomes as if they were uniformly important to all patients in the study. Very few studies take a personalized approach to patient outcomes, in which the outcomes of interest are those determined by each patient specific to their own circumstances and wishes.
Practice Implications
Psychotherapists who practice from an evidence-informed perspective often try to measure outcomes in their own practices using reliable measurements. However, many of these measurements may be too general for any specific patient, or they may represent outcomes that do not align with what the individual patient wants. Practicing clinicians who assess outcomes in their own practices, may want to consider supplementing standard symptom outcome measures with more personalized assessments for patients.
A Brave New World of Training and Consultation in Psychotherapy
Imel, Z. E., Pace, B. T., Soma, C. S., Tanana, M., Hirsch, T., Gibson, J., Georgiou, P., Narayanan, S., & Atkins, D. C. (2019). Design feasibility of an automated, machine-learning based feedback system for motivational interviewing. Psychotherapy, 56(2), 318–328.
I do not mean to conjure up the image of a dystopian future, but I could not resist the pithy title for this blog. Ideally, psychotherapists in training or those who seek professional development would receive high quality accurate feedback about their behavior (e.g., about interpersonal skills, empathy, vocal tone, body language) and competence (e.g., regarding specific interventions) in real time. This would allow psychotherapists and trainees can make fine-tuned adjustments to their behaviors and interventions that match or complement the specific patient with which they are working. But, given the current technology, this is impossible. Instead psychotherapy training and feedback to practicing clinicians is slow, cumbersome, and imprecise. Current supervision and consultation practices rely on giving feedback based on the clinician’s verbal case report or, at best, based on viewing video recordings. There are systems that provide feedback on patient outcomes that may alert psychotherapists to something going amiss in for the patient. But such feedback occurs post-session, is based on patient self-report, and does not inform immediate in-session therapist behaviors. In this study, Imel and colleagues evaluated an initial proof of concept of an automated feedback system that generated quality metrics about specific therapist interventions and about therapist skills like empathy. They used computer technology based on natural language processing to take conversational data from video of psychotherapy sessions in order to answer questions like: “what did the therapist and patient talk about during the session?”, “how empathic was the therapist?”, and “how often did the therapist use reflections versus closed questions in the session?” The authors developed a machine learning tool to transcribe, code, and rapidly generate feedback to 21 experienced and novice therapists who recorded a 10-minute session with a standardized patient (a standardized patient is an actor who loosely follows a script). The machine learning technology was accurate at defining or coding a “closed question” by a therapist (e.g., a question with a yes/no answer; inter rater agreement with a human coder ICC = .80), but not as accurate at defining or coding a therapist empathic statement (inter rater agreement with a human coder ICC = .23). The system provided immediate feedback the therapists about their behaviors during the session using graphics and text (fidelity to specific interventions, counseling style, empathy, percent open/closed questions, percent reflections). All therapists rated the tool as “easy to use”, 86% strongly agreed that the feedback was representative of their performance, 90% agreed that if the tool was available, they would use it in their clinical practice.
Practice Implications
Typically, professional consultation or supervision involves a consultant giving the therapist feedback based on imprecise descriptions of events in a therapy session that occurred at some point in the recent past. This method of training and consultation in psychotherapy has not changed much in the past 60 years. One key drawback of current methods of training and consultation is that they do not make use of real-time feedback to help therapist adjust behaviors to the specific patient or context. It is possible that in the near future with rapid advances in artificial intelligence and machine learning a therapist will be able to finish a session with a patient and receive an immediate feedback report about the previous hour. The feedback might include metrics on empathy, the percent of questions vs reflections, competence in specific interventions, among other personalize ratings. This future might also have novice trainees receive immediate real-time in-session feedback about behaviors of interest that need to be adjusted, or for which more training is necessary. For some, this might be a vision of a dystopian future, for others it may represent a way forward in which therapists achieve more refined skills and better patient outcomes.
January 2020
Cognitive Behavioral Analysis System of Psychotherapy (CBASP) for Chronic Depression
Cognitive Behavioral Analysis System of Psychotherapy (CBASP) for Chronic Depression
Schramm, E., Kriston, L., Zobel, I., Bailer, J., Wambach, K., …Harter, M. (2017). Effect of disorder-specific vs nonspecific psychotherapy for chronic depression: A randomized clinical trial. JAMA Psychiatry, 74, 233-242.
The lifetime prevalence of chronic depression is somewhere between 3% and 6% of the population. Chronic depression refers to depression that develops into a chronic course of more that 2 years. Compared to those with acute depression (< 2 years depressed), patients with chronic depression experience greater social, physical, and mental impairments. This large randomized controlled trial by Schramm and colleagues assessed the efficacy of the Cognitive Behavioral Analysis System (CBASP) compared to so-called non-specific psychotherapy (NSP), both delivered in 24 sessions. CBASP is a structured therapy that combines cognitive and interpersonal treatments focused on problems solving and learning the effects of one’s own behaviors on others. On the other hand, therapists delivering NSP were limited to reflective listening, empathy, and helping the client feel hopeful. Specific interventions associated with cognitive or interpersonal therapies were prohibited. A total of 262 patients with chronic depression were randomly assigned to receive 24 sessions of either CBASP or NSP. Main outcomes included indicators of “response” to treatment (a 50% reduction in a depression scale score) or “recovery” (a very low score on the scale at the end of treatment). Both CBASP and NSP resulted in a significant decline in depressive symptoms after 48 weeks. The CBASP condition was slightly more effective than simply providing NSP (d = 0.39, NNT = 5). About 38.7% responded to CBASP compared to 24.3% who responded to NSP (OR = 2.02; 95% CI, 1.09-3.73; p = .03; NNT = 5). In terms of remission, 21.8% recovered after CBASP compared to 12.6% in NSP (OR = 3.55; 95% CI, 1.61-7.85; p = .002; NNT = 4). Average drop-out rates were similar between the two treatments at about 22%.
Practice Implications
CBASP represents a highly structured integrative treatment for chronic depression. It did modestly better than NSP in which therapists were prohibited from engaging in any technical intervention. In the end, the longer-term rates of recovery for CBASP were also modest at about 21.8%. On the one hand, chronic depression is notoriously difficult to treat with psychotherapy or medications, so perhaps CBASP will provide relief for some. On the other hand, an average 21.8% recovery rate for CBASP was modest. CBASP was slightly better than providing active listening and empathy alone.
Adverse Events During Psychotherapy
Adverse Events During Psychotherapy
Meister, R., Lanio, J., Fangmeier, T., Harter, M., Schramm, E., … Kriston, L. (2020). Adverse events during a disorder‐specific psychotherapy compared to a nonspecific psychotherapy in patients with chronic depression. Journal of Clinical Psychology, 76, 7-19.
Adverse events refer to negative or unwanted outcomes of psychotherapy that may be due to the therapy itself when delivered correctly, or to the application of the therapy when delivered incorrectly. For example, patients may report worsening of symptoms, relationship problems with partners or family, problems at work, stigma, and other disadvantages. Adverse events during pharmacologic treatment are well studied and are often considered when making treatment decisions. However, adverse events in psychotherapy are largely ignored in the research and clinical literature. A recent meta analysis reported that the median deterioration rates in psychotherapy studies is about 4%, which is likely less than half the rate of deterioration seen in regular clinical practice. In this study, Meister and colleagues look at deterioration rates in a randomized controlled trial comparing the Cognitive Behavioral Assessment System of Psychotherapy (CBASP) versus non-supportive psychotherapy (NSP). In that study that was previously summarized in this blog, 262 depressed patients were randomly assigned to receive 24 weeks of either CBASP or NSP. Participants who received CBASP were slightly better off than those who got NSP, and the drop-out rates were equivalent between conditions. Therapists asked patients at each session if the patient experienced an adverse event in the previous week. Patients reported an average of about 12 adverse events during the 24 weeks of psychotherapy, and there was no difference in the number of adverse events between CBASP and NSP. However, patients receiving CBASP reported more severe adverse events related to their personal life and work life compared to patients receiving NSP. Suicidal thoughts were infrequently reported by patients, and their frequency did not differ between CBASP and NSP.
Practice Implications
The study highlights that symptoms and interpersonal conflicts may temporarily increase as a result of being in psychotherapy. The authors argued that the increases in problems with work and personal relationships may be due to the specific interpersonal treatment elements of CBASP that require changes in the patient’s interpersonal behaviors that temporarily may be disruptive to their lives. Therapists may consider informing patients about the possible temporary negative effects of psychotherapy on their relationships or functioning. This preparation might help patients to make informed decisions about psychotherapy and to prepare them to cope with changes in their relationships.
December 2019
Therapist Racial Microaggression and the Therapeutic Alliance
Owen, J., Tao, K. W., Imel, Z. E., Wampold, B. E., & Rodolfa, E. (2014). Addressing racial and ethnic microaggressions in therapy. Professional Psychology: Research and Practice, 45(4), 283–290.
Overt forms of racism and prejudice still occur in society, and less overt forms are likely more prevalent. Microaggression are those less overt forms of racism and prejudice that may include direct and indirect insults, slights, and discriminatory messages. Specific types of microaggression are: microinvalidations (e.g., denying that racism exists), microassaults (e.g., direct racism but done in private), and microinsults (e.g., believing a group’s cultural norms are pathological). Microaggression are by definition ambiguous and subtle, and they may target culture, race, gender, sexual orientation, and other group identities. Microaggressions are associated with psychological distress in the recipient. Microaggressions can also occur in therapy if a patient perceives a therapist’s dismissing or negating messages about the patient’s culture, or if a therapist engages in culturally inappropriate interventions. Microaggressions represent a special type of therapeutic alliance rupture that could lead to negative patient outcomes. It is also possible that therapists and clients who address microaggressions after they occur are capable of repairing the alliance rupture and moving forward with a stronger relationship. However, there is very little research of the impact of client perceived microaggressions on the therapeutic alliance. In this unique study, Owen and colleagues asked 120 racial and ethnic minority university counselling centre patients treated by 33 different therapists (23 of whom were White) to rate their experience microaggressions, to indicate if the microaggression was discussed, and to rate the therapeutic alliance. In total, 53.3% of patients experienced a microaggression in therapy, and of those patients, 68.4% were treated by a racial or ethnic minority therapist. Clients who reported fewer microaggressions also reported stronger therapeutic alliances (r = .28, p = .01). Of the patients who reported a microaggression, only 24% (13 patients) reported that the microaggression was discussed by the therapist. Of these 13 patients, almost all (12 patients) reported that the discussion was successful. Therapist and patient dyads who successfully discussed the microaggression: (1) had alliance scores comparable to patients who did not experience a microaggression, and (2) had alliance scores that were significantly higher than dyads who experienced but did not discuss the microaggression.
Practice Implications
Microaggressions appear to be ubiquitous in daily life and in psychotherapy – no therapist is immune. More than 53% of patients in this study reported a microaggression, despite what was likely their therapists’ good intentions. Microaggression are a special case of therapeutic alliance ruptures, which are known to be associated with poor patient outcomes. Therapists must develop a strong multicultural orientation and take a culturally humble stance with clients from a different culture or group. This involves therapists being attuned to the possibility of committing a microaggression, inviting patients to alert the therapist should a microaggression occur, and being open to clarifying misunderstandings and owning missteps.