Blog
The Psychotherapy Practice Research Network (PPRNet) blog began in 2013 in response to psychotherapy clinicians, researchers, and educators who expressed interest in receiving regular information about current practice-oriented psychotherapy research. It offers a monthly summary of two or three published psychotherapy research articles. Each summary is authored by Dr. Tasca and highlights practice implications of selected articles. Past blogs are available in the archives. This content is only available in English.
This month...
…I blog about content from the updated edition of the Handbook of Psychotherapy and Behavior Change, published in 2021: are psychological therapies efficacious, is one therapy more effective, and how much therapy is necessary.
Type of Research
Topics
- ALL Topics (clear)
- Adherance
- Alliance and Therapeutic Relationship
- Anxiety Disorders
- Attachment
- Attendance, Attrition, and Drop-Out
- Client Factors
- Client Preferences
- Cognitive Therapy (CT) and Cognitive-Behavioural Therapy (CBT)
- Combination Therapy
- Common Factors
- Cost-effectiveness
- Depression and Depressive Symptoms
- Efficacy of Treatments
- Empathy
- Feedback and Progress Monitoring
- Group Psychotherapy
- Illness and Medical Comorbidities
- Interpersonal Psychotherapy (IPT)
- Long-term Outcomes
- Medications/Pharmacotherapy
- Miscellaneous
- Neuroscience and Brain
- Outcomes and Deterioration
- Personality Disorders
- Placebo Effect
- Practice-Based Research and Practice Research Networks
- Psychodynamic Therapy (PDT)
- Resistance and Reactance
- Self-Reflection and Awareness
- Suicide and Crisis Intervention
- Termination
- Therapist Factors
- Training
- Transference and Countertransference
- Trauma and/or PTSD
- Treatment Length and Frequency
December 2021
Routine Outcome Monitoring
Lutz, W., de Jong, K., Rubel, J.A., & Delgadillo, J. (2021). Measuring, predicting, and tracking change in psychotherapy. In M. Barkham, W. Lutz, and L.G. Castonguay (Eds.) Bergin and Garfield’s Handbook of Psychotherapy and Behavior Change (7th ed.). Wiley. Chapter 4.
Routine outcome monitoring is also known as progress monitoring and feedback. This involves regularly assessing patients with a psychometrically reliable scale before a therapy session and providing the therapist with feedback on the patient’s progress. The feedback includes how the patient is doing relative to the average patient, and how the patient is doing in this session relative to their own scores in previous sessions. By doing this, therapists can get regular and reliable information about their patient’s progress and be alerted to when the patient is not on track to improve or is getting worse. Decisions about patient improvement on a session-to-session basis are complex because they involve knowing how the patient is doing regarding symptoms, quality of life, and relationship functioning relative to other patients and relative to their own functioning in the past. No wonder therapists often mis-judge when a patient is getting worse. Routine outcome monitoring involves decision-making tools to enhance a clinician’s decisions – like the way a physician uses a blood test or x-ray to enhance their clinical observations. In this part of the chapter, Lutz and colleagues review the research over the past 50 years on outcome monitoring and feedback. The effects of psychotherapy with feedback compared to psychotherapy without feedback ranges from small (g = .07) to medium (d = .40) in size. These effects seem small, but the authors remind us that feedback is a relatively simple clinical tool provided in addition to psychotherapy, and so these positive effects occur are over and above the general effectiveness of psychotherapy. Highest effect sizes are achieved for clients who are not on track (likely to get worse) such that feedback compared to no feedback in these not-on-track patients result in effect sizes ranging from 0.36 to 0.53, indicating a moderate to large effect. Further, when feedback was provided, patient dropout was reduced by 20% compared to when feedback was not provided.
Practice Implications
Although routine outcome monitoring is relatively easy to use, there are barriers to their implementation. Organizational cultures are difficult to change, and resources must be assigned to implement these strategies. Clinicians must have the technology, some training, and funds to purchase the psychometric scales which may be a challenge for some. And attitudinal barriers are a problem if managers or clinicians do not value outcome measurement. Nevertheless, patient reported outcomes with psychometrically valid scales should be central to ensure good patient-centered care. Psychotherapists can benefit from quality information to help their clinical decision making, especially when it comes to identifying patients who might not be benefitting. Such feedback about patients who are at risk of getting worse may help clinicians to adjusting treatment and their interpersonal stances to these patients.
November 2021
Psychological Treatments for Panic Disorder
Papola, D., Ostuzzi, G., Tedeschi, F., Gastaldon, C., Purgato, M., Del Giovane, C., . . . Barbui, C. (2021). Comparative efficacy and acceptability of psychotherapies for panic disorder with or without agoraphobia: Systematic review and network meta-analysis of randomised controlled trials. The British Journal of Psychiatry, 1-13. doi:10.1192/bjp.2021.148
Panic disorder affects between 1.1% and 3.7% of the population, and panic symptoms can occur in about 10% of patients in primary care. Panic disorder is characterized by recurrent and unexpected panic attacks including heart palpitations, sweating, and trembling. Often, the fear of panic attacks results in avoidance of places or situations that might cause another panic attack. Sometimes, panic attack co-occurs with agoraphobia, or anxiety related to being in certain places or situations. Panic disorder can be debilitating and can also co-occur with depression or substance use disorders. In this network meta-analysis, Papola and colleagues systematically reviewed 136 randomized controlled trials of psychological therapies for panic disorder that included over 7,300 patients. The therapies included CBT, psychodynamic therapy, behavior therapy, EMDR and others that were compared to each other and treatment as usual (which often included minimal intervention). The most effective treatments compared to treatment as usual were CBT (SMD = -0.67, 95%CI: -0.95 to -0.39) and short term psychodynamic therapy (SMD = -0.61, 95%CI: -1.15 to -0.07). All other psychotherapies (EMDR, IPT, behavior therapy, third wave CBT, cognitive therapy, psychoeducation) were not more effective than treatment as usual. The authors also evaluated acceptability of the treatment to patients, which they defined as the dropout rates from the therapies that were offered. Behavior therapy and cognitive therapy were less accepted by patients than short term psychodynamic therapy and CBT.
Practice Implications
The results of this large network meta-analysis indicates that CBT and short-term dynamic therapy are efficacious treatments for panic disorder. The authors suggest that these treatments should be considered as first line interventions. These findings confirm a growing trend indicating the efficacy of psychodynamic therapies for panic and as well as for other common mental disorders.
October 2021
Sustained Response to Antidepressants and Psychotherapy
Furukawa, T.A., Shinohara, K., Sahker, E., Karyotaki, E., Miguel, C., ….Cuijpers, P. (2021). Initial treatment choices to achieve sustained response in major depression: A systematic review and network meta-analysis. World Psychiatry, 20, 387-396.
Two common treatments for major depression are antidepressant medications and psychotherapy, both of which have been tested in randomized controlled trials. Antidepressants are among the most prescribed medications, and an increasing number of patients are on longer-term use of these medications. However, it is unclear as to whether choosing antidepressant medication or psychotherapy at the beginning or the acute phase of depression will lead to a sustained response in the longer term. In this network meta-analysis, Furukawa and colleagues examine the important question: “which therapies can get me well and keep me well?” The authors selected randomized controlled studies in which antidepressants or psychotherapy, or their combination were prescribed and compared to each other or to a control condition (treatment as usual or placebo pill). In these studies, adult participants with major depression remained in the treatment or control condition up to 12 months post-treatment. Psychotherapies included many known treatments like CBT, behavioral activation, psychodynamic therapy, and interpersonal psychotherapy. This network meta-analysis included 81 trials representing over 13,000 patient participants. Combined psychotherapy plus antidepressant medication resulted in a more sustained response to treatment (better outcomes) in the long run than control comparisons (OR: 2.52, 95% CI: 1.66, 3.85). Psychotherapy alone was more effective in the long run than pharmacotherapy alone (OR: 1.53, 95% CI: 1:00 – 2.35). The advantage of combined treatment over antidepressants alone was about 14% to 16%, whereas the advantage of psychotherapy over antidepressants was about 12%. There were no differences in longer term effectiveness among the different types of psychotherapy.
Practice Implications
This study shows that the effects of psychotherapy when initiated in the acute phase of major depression (at the outset of symptoms) are enduring over a longer time frame. Psychotherapies outperformed antidepressant medications, standard treatment, and pill placebo. The results also suggested that adding pharmacotherapy to psychotherapy did not interfere with the enduring effects of psychotherapy. The authors suggest that treatment guidelines for depression should be updated to emphasize psychotherapy as the preferred initial treatment option.
The Therapeutic Alliance in Treating Posttraumatic Stress Disorder
Howard, R., Berry, K., & Haddock, G. (2021). Therapeutic alliance in psychological therapy for posttraumatic stress disorder: A systematic review and meta-analysis. Clinical Psychology and Psychotherapy.
The therapeutic alliance is a key therapeutic factor with a lot of research support. The alliance is the collaborative agreement between patient and therapist on the goals and tasks of therapy, and their emotional bond. A meta-analysis of 295 studies reported that the alliance is moderately and reliably related to patient outcomes, and that this effect cuts across therapy modalities, orientations, and diagnoses. Some clinical writers expressed concern that the alliance is more difficult to develop with patients with posttraumatic stress disorder (PTSD) because of psychological consequences of PTSD like avoidance, mistrust, emotion regulation problems that pose a barrier to developing an alliance. Further, the disrupted interpersonal relationships that is part of the PTSD experience may also inhibit the development of an alliance with a therapist. However, one could also argue that a strong therapeutic alliance that is characterized by an emotional bond between client and therapist might be highly therapeutic for patients with PTSD. This meta-analysis by Howard and colleagues is the first to systematically review the research on the association between the therapeutic alliance and patient outcomes following PTSD treatment. The meta-analysis included 12 studies of adults receiving treatment for PTSD. The aggregated correlation effect size was r = -.339 (95% CI: -0.436, -0.234) with low levels of heterogeneity among the studies indicating that the findings are reliable. The average effect size was moderate in size, robust to effects of an outlier, and there was little evidence of publication bias. The authors also conducted a sub analysis that indirectly compared in-person therapy (k = 8; r = -.323) to remote therapy (k = 4; r = -.390) in which they found no significant differences (Q(1) = 0.41, p = .524) in the alliance-outcome association.
Practice Implications
The findings add support to the larger research literature in psychotherapy about the importance of the therapeutic alliance to patient outcomes. In particular, the findings suggest that clinicians should develop a good therapeutic alliance when treating patients with PTSD in order to promote better outcomes. That is, therapists and clients must come to a collaborative agreement on what the goals of the therapy are and how the therapy will be conducted. In addition, developing an interpersonal therapeutic bond will help the patient to weather the challenges that are associated some PTSD treatments. The findings also suggested that the effect of the alliance was as strong when therapy was in-person versus remote – but this finding is not as reliable given the indirect nature of the comparisons.
September 2021
Mindfulness-Based Interventions Among People of Color
Sun, S., Goldberg, S.B., Loucks, E.B., & Brewer, J.A. (2021). Mindfulness-based interventions among people of color: A systematic review and meta-analysis, Psychotherapy Research, DOI: 10.1080/10503307.2021.1937369.
In the United States, people of color (POC) are disproportionately affected by structural inequalities related to racism such as high rates of incarceration, poor housing, and economic difficulties. Racial disparities also exist in health care such that POC are less likely to use health services thus resulting in more persistent health problems. Research has shown that mindfulness-based interventions (MBIs) may be effective in improving health outcomes of conditions that are prevalent among POC like psychiatric symptoms and cardiovascular disease. Some argue that MBIs are especially culturally relevant to POC because of the focus on overall well-being, the emphasis on resilience, and communally delivered formats. In this meta-analysis, Sun and colleagues systematically reviewed 24 randomized controlled trials with a total of over 2000 participants in which MBI was compared to no treatment or to an active control (a control group that was meant to be therapeutic). Only trials in which the study sample was predominantly (>75%) POC were included. At post-treatment, MBIs showed small but statistically significant outcomes compared to active controls (k = 16, g = 0.11, 95% CI = [0.04, 0.18], p = .002) and to no treatment (k=8, g = 0.26, 95%CI = [0.07, 0.45], p = .007). These are smaller effects than reported in other populations. Drop-out rates for POC receiving MBI was about 22%, which is similar to what is reported in the general psychotherapy outcome literature.
Practice Implications
The results suggest a modest effect of MBI for POC, and that the effects may be smaller than reported in studies with other populations. Only two of the studies reported culturally adapting MBI for POC. Psychotherapists might consider cultural adaptation of MBI or providing MBI from a multi-cultural orientation framework that includes therapists’ cultural humility, making the best of cultural opportunities in therapy, and developing cultural comfort and competence.
August 2021
What Proportion of Patients Benefit from Short-Term Psychotherapy?
Cuijpers, P., Karyotaki, E., Ciharova, M., Miguel, C., Hisashi, N., &Furukawa, T.A. (2021). The effects of psychotherapies for depression on response, remission, reliable change, and deterioration: A meta-analysis. Acta Psychiatrica Scandinavica, 10.1111/acps.13335. Advance online publication.
Many meta-analyses report that psychological therapies are effective to treat depression, that there are no differences between types or orientations of therapy in their outcomes, and that psychotherapy is as effective as medications in the short term and perhaps more effective in the longer term. But what do these findings mean for everyday practice? Many meta-analyses report a standardized mean effect size between treatment and control conditions. However, the effect size is an abstraction that may be difficult to interpret unless you understand the statistic. Clinicians may ask a more practical question: what is the proportion of patients that improve (have meaningful reductions in depression scores) and recover (improved and no longer are depressed)? This meta-analysis by Cuijpers and colleagues of 228 studies representing over 23,000 adult patients looked at the proportion of patients who improved and recovered after psychotherapy relative to those in control conditions (no treatment, care as usual, pill placebo). The psychotherapies were short term manualized treatments like CBT, behavioral activation, interpersonal psychotherapy delivered in individual, group, and self-help formats. About 41% of patients improved with psychotherapy for depression compared to 17% that improved with usual care and 31% for pill placebo. However, after statistically controlling for publication bias (i.e., the likelihood that some unflattering studies were never published), the improvement rate for psychotherapy was 38%. Recovery rates for psychotherapy ranged from 26% to 34%, and recovery in the control conditions ranged from 9% to 17%. There were no differences between therapy orientations. Highest rates of recovery or improvement were achieved by individual therapy and the lowest rates were seen in guided self-help. Deterioration rates were just below 5% in psychotherapy and about 7% to 13% in control conditions.
Practice Implications
The effects of time-limited manualized psychotherapies tested in randomized controlled trials were modest. About 40% of patients improved and about 30% recovered. On the positive side, psychotherapies resulted in only about 5% of patients getting worse. The authors argued that clinicians must consider more effective strategies beyond these approaches to improve outcomes for depression. Some have focused on improving psychotherapist effectiveness, rather than on specific interventions. Methods like progress monitoring, managing countertransference, and repairing therapeutic alliance ruptures are means of improving psychotherapists’ effectiveness.